Indinavir and Rifabutin Drug Interactions in Healthy Volunteers
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چکیده
منابع مشابه
Indinavir and rifabutin drug interactions in healthy volunteers.
Two studies examined the pharmacokinetics of indinavir and rifabutin when coadministered in healthy subjects. Rifabutin, which induces the expression of cytochrome P450 (CYP) 3A, and indinavir, which inhibits that enzyme system, are frequently coadministered in patients infected with HIV. The second study was undertaken to determine if altering the dose of rifabutin coadministered with indinavi...
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ژورنال
عنوان ژورنال: The Journal of Clinical Pharmacology
سال: 2004
ISSN: 0091-2700
DOI: 10.1177/0091270003262807